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The Papovaviridae: The Polyomaviruses (The Viruses) download epub

by Norman P. Salzman


Epub Book: 1871 kb. | Fb2 Book: 1658 kb.

What was startling was that these biologic properties are associated with viruses that contain genetic in­ formation that is able to code for only five or six proteins.

Softcover 64,99 €. price for Russian Federation (gross). What was startling was that these biologic properties are associated with viruses that contain genetic in­ formation that is able to code for only five or six proteins. Since that time, investigations with these viruses have been in four principal areas. One major area of study has been on cells transformed by viruses that show altered growth properties and specify new viral and cellular proteins.

The Papovaviridae : The Polyomaviruses. The studies that have medical relevance concern JC and BK viruses and there is evidence of widespread exposure of human populations to these agents.

oceedings{Howley1987TheP, title {The Papovaviridae}, author {Peter M Howley and N. P. Salzman and Helena Ahola}, booktitle {The Viruses}, year {1987} }. Peter M Howley, N. Salzman, +1 author Helena Ahola. Published in The Viruses 1987. Proceedings of the National Academy of Sciences of the United States of America. Isabelle Giri, Olivier Danos, M. Yaniv.

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Polyomaviridae is a family of viruses whose natural hosts are primarily mammals and birds. As of the most recent (2018) taxonomy release by the International Committee on Taxonomy of Viruses, there were 89 recognized species in this family contained. As of the most recent (2018) taxonomy release by the International Committee on Taxonomy of Viruses, there were 89 recognized species in this family contained within four genera, as well as 9 species that could not be assigned to a genus. 13 species are known to infect humans, while others, such as Simian Virus 40, have been identified in humans to a lesser extent

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In addition, evidence has now established their role in non-melanoma skin cancers, head and neck cancer (HNC), and the development of other anogenital malignancies.

The Papovaviridae Vol. 1 : The Polyomaviruses. Book Overview Since that time, investigations with these viruses have been in four principal. It has been more than twenty years since the isolation of polyoma virus and SV40, and the reports that they could produce tumors in animals and transformation of cells in culture. What was startling was that these biologic properties are associated with viruses that contain genetic in- formation that is able to code for only five or six proteins.

Within the mucosal HPV, there is a group associated with cervical cancer.

It has been more than twenty years since the isolation of polyoma virus and SV40, and the reports that they could produce tumors in animals and transformation of cells in culture. What was startling was that these biologic properties are associated with viruses that contain genetic in­ formation that is able to code for only five or six proteins. Since that time, investigations with these viruses have been in four principal areas. One major area of study has been on cells transformed by viruses that show altered growth properties and specify new viral and cellular proteins. Transformation studies have focused on the tumor (T) antigens that are specified by the virus and are required to initiate and to maintain the transformed state. Current studies on transformation are summarized in Chapter 4. The second broad area of investigation concerns replication of viruses during a lytic cycle of infection. T-antigens that are the hallmark of transformed cells are also expressed in cells that are lytically infected and are required for viral DNA replication and also function to alter rates of transcription of the early and late viral genes. Except for T-antigen, virus replication depends on the cellular enzymatic machinery and so the description of viral macromolecular synthesis has provided valuable insights into the cellular biosynthetic pathways. These studies are described in Chapters 1-3. The studies that have medical relevance concern JC and BK viruses and there is evidence of widespread exposure of human populations to these agents.
The Papovaviridae: The Polyomaviruses (The Viruses) download epub
Medicine
Author: Norman P. Salzman
ISBN: 0306423081
Category: Medical Books
Subcategory: Medicine
Language: English
Publisher: Springer; 1986 edition (October 31, 1986)
Pages: 474 pages