» » Antimetabolites of Nucleic Acid Metabolism (English and German Edition)

Antimetabolites of Nucleic Acid Metabolism (English and German Edition) download epub

by T.A. Scott,Peter Langen


Epub Book: 1473 kb. | Fb2 Book: 1863 kb.

Peter Langen, Thomas A. Scott}, author {Arthur Kornberg}, year {1977} }. Arthur Kornberg.

Antimetabolites of Nucleic Acid Metabolism. Select Format: Hardcover. ISBN13:9780677307602. Release Date:January 1975.

Start by marking Antimetabolites of Nucleic Acid Metabolism: The .

Start by marking Antimetabolites of Nucleic Acid Metabolism: The Biochemical Basis of Their Action, with Special Reference to Their Application in Cancer Therapy as Want to Read: Want to Read savin. ant to Read. See a Problem? We’d love your help. Details (if other): Cancel.

New Biological Books. Antimetabolites of Nucleic Acid Metabolism. Peter Langen, Thomas A. Scott. Arthur Kornberg, "Antimetabolites of Nucleic Acid Metabolism.

An antimetabolite is a chemical that inhibits the use of a metabolite, which is another chemical that is part of normal metabolism

An antimetabolite is a chemical that inhibits the use of a metabolite, which is another chemical that is part of normal metabolism. Such substances are often similar in structure to the metabolite that they interfere with, such as the antifolates that interfere with the use of folic acid; thus, competitive inhibition can occur, and the presence of antimetabolites can have toxic effects on cells, such as halting cell growth and cell division, so these compounds are used as chemotherapy for cancer.

An antimetabolite is a chemical that inhibits the use of a metabolite, which is another chemical that is part of normal metabolism. Such substances are often similar in structure to the metabolite that they interfere with, such as the antifolates that interfere with the use of folic acid

ANTIMETABOLITES (Greek anti-against + a metabolite) - substances which owing to the structural proximity or bigger activity in relation to natural metabolic products (metabolites) can replace them in biochemical reactions. However, having certain.

ANTIMETABOLITES (Greek anti-against + a metabolite) - substances which owing to the structural proximity or bigger activity in relation to natural metabolic products (metabolites) can replace them in biochemical reactions. However, having certain differences in a structure of a molecule, And. cannot provide the further normal course of these reactions, than and cause change of processes of a metabolism. The major group A. make structural analogs vitamins (see), hormones (see) and mediators (see).

Antimetabolites disrupt nucleic acid synthesis by interfering with production of a major nucleotide metabolite or by substituting for the natural metabolite. Like most cytotoxic anticancer agents, antimetabolites are toxic to normal cells, especially those in the bone marrow and gastrointestinal tract. Although the enzymes inhibited by antimetabolites are also present in normal cells, some selectivity toward cancer cells is possible due to their faster division rates. Most antimetabolites interfere with nucleic acid synthesis and for this reason we will study in this chapter the antitumor compounds that hamper the production of DNA or RNA by a variety of mechanisms including: a.

Study Flashcards On Antimetabolites and drugs affecting nucleic acid metabolism at Cram. Quickly memorize the terms, phrases and much more. com makes it easy to get the grade you want!

Metabolism of the nucleic acids of rumen bacteria by preruminant and ruminant lambs

British Journal of Nutrition. Metabolism of the nucleic acids of rumen bacteria by preruminant and ruminant lambs. British Journal of Nutrition, Vol. 45, Issue. 1. Concentrations of nucleic acid nitrogen and other nitrogenous constituents were estimated in digesta taken from the proximal duodenum of calves which were given, either, one of a number of stall diets or pasture. These concentrations were compared, using polyethylene glycol (PEG) as a non-absorbed marker, with corresponding concentrations in rumen fluid and ileal contents.


Antimetabolites of Nucleic Acid Metabolism (English and German Edition) download epub
Biological Sciences
Author: T.A. Scott,Peter Langen
ISBN: 0677307608
Category: Science & Math
Subcategory: Biological Sciences
Language: English German
Publisher: Gordon & Breach Science Publishers Ltd (December 8, 1975)
Pages: 286 pages