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Computational Biology of Transcription Factor Binding (Methods in Molecular Biology) download epub

by Istvan Ladunga


Epub Book: 1260 kb. | Fb2 Book: 1579 kb.

Authoritative and easy to use, Computational Biology of Transcription Factor Binding guides scientists working in this area and demands not only new . Methods in Molecular Biology.

Authoritative and easy to use, Computational Biology of Transcription Factor Binding guides scientists working in this area and demands not only new experiments but also the re-annotation of existing experimental data and computational predictions leading to important ongoing, major paradigm changes for us al.

University of Nebraska at Lincoln. Written for the highly successful Methods in Molecular Biology™ series, this work provides the kind of detailed description and implementation advice that is crucial for getting optimal results in the lab. Authoritative and easy to use, Computational Biology of Transcription Factor Binding guides scientists working in this area and demands not only new experiments but also the re-annotation of existing experimental data and computational predictions leading to important ongoing, major paradigm changes for us all.

Computational Biology of Transcription Factor Binding Methods in Molecular Biology.

relational Transcription Factor Database (TFD) including large. collection of regulatory factors and their binding sites was cre-. ated by Gosh (19,20). Over 7,900 sequences of transcrip

Автор: Ladunga Название: Computational Biology of Transcription Factor Binding ISBN: 1607618532 . Описание: Identification of differentially expressed genes is one of the major challenges in molecular biology.

Описание: Authoritative and easy to use, this volume examines the computational analysis of the biological interpretations of transcription factor binding. This technique has been proven to be highly effective in identifying sequences that are differentially expressed in various cell types.

Computational Biology of Transcription Factor Binding (Methods in Molecular Biology, Vol. 674). Download (pdf, . 8 Mb) Donate Read.

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Molecular biology /məˈlɛkjʊlər/ is a branch of biology that concerns the molecular basis of biological activity between biomolecules in the various systems of a cell, including the interactions between DNA, RNA, proteins and their biosynthesis, as w. .

Molecular biology /məˈlɛkjʊlər/ is a branch of biology that concerns the molecular basis of biological activity between biomolecules in the various systems of a cell, including the interactions between DNA, RNA, proteins and their biosynthesis, as well as the regulation of these interactions

Identification of transcription factor binding sites derived from . Methods in molecular biology - 674, Springer protocols, Methods in molecular biology (Clifton, . - v. 67. Springer protocols.

Identification of transcription factor binding sites derived from transposable element sequences using ChIP-seq, Andrew B. Conley and I. King Jordan. Target gene identification via nuclear receptor binding site prediction, Gabor Varga Practical computational methods for regulatory genomics : a cisGRN-lexicon and cisGRN-browser for gene regulatory networks, Sorin Istrail.

A Systems’ Biology Approach to Study MicroRNA-Mediated Gene Regulatory Networks, Xin Lai, Animesh Bhattacharya, Ulf .

Transcriptional regulation controls the basic processes of life. Its complex, dynamic, and hierarchical networks control the momentary availability of messenger RNAs for protein synthesis. Transcriptional regulation is key to cell division, development, tissue differen- ation, and cancer as discussed in Chapters 1 and 2. We have witnessed rapid, major developments at the intersection of computational biology, experimental technology, and statistics. A decade ago, researches were struggling with notoriously challenging predictions of isolated binding sites from low-throughput experiments. Now we can accurately predict cis-regulatory modules, conserved cl- ters of binding sites (Chapters 13 and 15), partly based on high-throughput ch- matin immunoprecipitation experiments in which tens of millions of DNA segments are sequenced by massively parallel, next-generation sequencers (ChIP-seq, Chapters 9, 10, and 11). These spectacular developments have allowed for the genome-wide mappings of tens of thousands of transcription factor binding sites in yeast, bacteria, mammals, insects, worms, and plants. Please also note the no less spectacular failures in many laboratories around the world.
Computational Biology of Transcription Factor Binding (Methods in Molecular Biology) download epub
Biological Sciences
Author: Istvan Ladunga
ISBN: 1607618532
Category: Science & Math
Subcategory: Biological Sciences
Language: English
Publisher: Humana Press; 2010 edition (September 13, 2010)
Pages: 454 pages